[Mobhack]

Have you tried windowed mode at desktop resolution?. (Not full-screen mode - that is only for legacy computers, modern day video cards often have problems with full-screen 256 colour mode).

I think others have had the game running on the new ultra resolution monitors, beyond 1080P resolution, but maybe not ones with such a pixel count. I'm sure those guys will pitch in.

Try changing the monitor's resolution downwards is my best guess. Start with 1920x1080 and work uwards till you find a limit where it cannot drive the monitor is likely your best approach. There may well be some hard upper limit for DirectX3 or 4 (which the third-party video driver we use is written in).