on a purely personal note, I dislike bless strategies.  I enjoy well rounded way more.  
I generally play SP (so far I suck at my first 2 MP games 

.  My fav so far is Tien Chi with a rainbow pretender and luck scales - full magic access (although I'll take a couple slots of blood I only use it late game for a few items when I can take the time out to hunt).
Enjoyment > optimization in SP for me